ESC Congress 2026 · Munich · 28–31 August

预防心脏病学

PREVENTIVE CARDIOLOGY
9重点场次
1Hot Line
3新指南
3中国专家参与
101中国报告
26卫星会系列
01重点学术场次Priority Sessions9 场
本专题的重点场次包含 Hot Line、LBCS、New ESC Guidelines、Ask the Trialists、Guidelines in Practice、Great Debates 等。
指南与标准3 场
New Guidelines
2026 ESC 心脏康复指南
2026 ESC Guidelines on Cardiac Rehabilitation
08-31 11:152026 ESC 心脏康复指南ESC 官网
08-31 13:002026 ESC 心脏康复指南 · 工作组答疑ESC 官网
08-31 14:152026 ESC 心脏康复指南 · 临床实践ESC 官网
血脂管理2 场
LBCS
2026 预防前沿:人工智能、肥胖与个体化心血管照护
Prevention in 2026: artificial intelligence, obesity and personalised cardiovascular care
时间08-30 08:15
主席Martha Gulati; Victor Aboyans
个体斑块阈值:用于选择个体化 LDL 目标以实现心血管预防个性化的因果 AI 生物世界模型
The Personal Plaque Threshold: A Causal AI Biological World Model for Selecting Individualized LDL Targets to Personalize Cardiovascular Prevention
Brian A Ference · 讲者 · University of Cambridge·08-30 08:15
全球首发
β受体阻滞剂与缺血性卒中风险:来自随机临床试验的证据
Risk of Ischemic Stroke With Beta-Blockers: Evidence From Randomized Clinical Trials
Franz Messerli · 讲者 · Lucerne Cantonal Hospital·08-30 08:15
全球首发
替尔泊肽治疗肥胖成人中按体重减轻维持程度分层的心血管代谢参数:SURMOUNT MAINTAIN 试验事后分析
Cardiometabolic parameters by the degree of maintenance of weight reduction in tirzepatide-treated adults with obesity: post hoc study of SURMOUNT MAINTAIN Trial
Luke Joseph Laffin · 讲者 · Cleveland Clinic·08-30 08:15
全球首发
高强度间歇训练降低老年人 10 年死亡率:Generation 100 随机对照试验
High-Intensity Interval Training Reduces 10-Year Mortality in Older Adults: The Generation 100 Randomized Controlled Trial
Sindre Midttun · 讲者 · Norwegian University of Science and Technology·08-30 08:15
全球首发
基于机器学习与血流动力学特征的临床决策支持系统用于基层个体化、符合指南的降压治疗(LIGHT-precision)
Machine learning and hemodynamic profile-based clinical decision support systems for personalized guideline-concordant antihypertensive treatment in primary care (LIGHT-precision)
Xin Zheng · 讲者 · 中国医学科学院阜外医院·08-30 08:15
中国全球首发
慢性冠脉综合征伴既往心肌梗死患者停用 β 受体阻滞剂:ABYSS 与 SMART-DECISION 随机试验的汇总分析
BetaBlocker discontinuation in patients with chronic coronary syndrome, prior myocardial infarction: a pooled analysis of the ABYSS and SMART-DECISION randomised trials.
Johanne Silvain · 讲者 · Pitie-Salpetriere Hospital (APHP)·08-30 08:15
全球首发
LBCS
他汀之后:下一代降脂疗法
Beyond statins: the next wave of lipid-lowering therapies
时间08-31 08:15
主席Marianne Benn; Florian Kronenberg
高危与极高危心血管风险患者中 inclisiran 对比贝派地酸降低 LDL-C 的头对头比较:4 期 VICTORION-CHALLENGE 试验结果
Head-to-head comparison of inclisiran vs bempedoic acid for LDL C lowering in patients with high and very high cardiovascular risk: Results from the phase 4 VICTORION-CHALLENGE trial
Ingo Hilgendorf · 讲者 · Charité·08-31 08:15
全球首发
口服 HRS-5346(新型小分子脂蛋白(a) 抑制剂)用于脂蛋白(a) 升高且高心血管风险的成人:2 期随机双盲研究
Oral HRS-5346, a novel small molecule lipoprotein(a) inhibitor, in adults at high cardiovascular risk with elevated lipoprotein(a): a phase 2, randomized, double-blind study
Dan Zhu · 讲者 · 北京大学第三医院·08-31 08:15
中国全球首发
急性冠脉综合征患者的方案化早期强化血脂管理(BRIDGE):多中心前瞻性整群随机对照试验
Protocol-based early intensive lipid management in patients with acute coronary syndrome (BRIDGE): A multicenter prospective cluster-randomized controlled trial
Kazuma Oyama · 讲者 · Tohoku University·08-31 08:15
全球首发
评估 VSA003 注射液治疗中国纯合子家族性高胆固醇血症(HoFH)青少年与成人疗效和安全性的 3 期临床试验
A phase 3 clinical trial to evaluate the efficacy and safety of vsa003 injection in chinese adolescents and adults with homozygous familial hypercholesterolaemia (hofh)
Zhuang Tian · 讲者 · 北京协和医院·08-31 08:15
中国全球首发
依洛尤单抗对无既往心肌梗死或卒中患者致死性结局的影响:VESALIUS-CV 试验预设分析
Effects of Evolocumab on Fatal Outcomes in Patients Without a Prior Myocardial Infarction or Stroke : Pre-specified Analysis of the VESALIUS-CV Trial
Robert Giugliano · 讲者 · Brigham and Women's Hospital·08-31 08:15
全球首发
长效靶向脂蛋白(a) 的 siRNA 药物 lepodisiran 对氧化磷脂的影响
Effect on Oxidized Phospholipids of Lepodisiran, an Extended Duration siRNA Targeting Lipoprotein(a)
Steven E Nissen · 讲者 · Cleveland Clinic Hospital·08-31 08:15
全球首发
风险预测与早筛1 场
Great Debates
焦点辩论:人工智能时代冠状动脉 CT 与心血管病预防
Great Debates: coronary computed tomography for cardiovascular disease prevention in the era of artificial intelligence
时间08-28 08:15
主席Kristina Haugaa
冠状动脉 CT 应用于增强心血管疾病预防
Coronary computed tomography should be used to enhance cardiovascular disease prevention
正方Charalambos AntoniadesUniversity of Oxford反方Birgitta VelthuisUniversity Medical Center Utrecht评论员Erin MichosThe Johns Hopkins University School of Medicine
冠状动脉 CT 应用于 veteran 运动员筛查
Coronary computed tomography should be used for screening veteran athletes
正方Sanjay SharmaCity St George's University of London反方Andre La GercheSt Vincent's Hospital评论员Silvia CastellettiUniversity Hospital Santa Maria della Misericordia
肥胖与代谢新药(GLP-1)1 场
Great Debates
焦点辩论:GLP-1 受体激动剂应否用于人群水平预防
Great Debate: should GLP-1 receptor agonists be used for population-level prevention?
时间08-30 11:00
主席Anne Tybjaerg-Hansen; Francesco Cosentino
GLP-1 受体激动剂应否用于人群水平预防
Should GLP-1 receptor agonists be used for population-level prevention?
正方John Eric DeanfieldUniversity College London反方Pasquale Perrone-FilardiUniversity of Naples Federico II评论员Marianne BennRigshospitalet
其他2 场Hot Line 1
LBCS
晚期临床试验:基因与分子疗法改写心血管疾病
Late-Breaking Clinical Trials: rewriting cardiovascular disease on gene and molecular therapies
时间08-28 16:15
主席Silvia Giuliana Priori; Steven E Nissen
血管生成素样蛋白 3 抗体 rivocibart 治疗纯合子家族性高胆固醇血症
Angiopoietin-like 3 antibody rivocibart for homozygous familial hypercholesterolemia
Daoquan Peng · 讲者 · 中南大学湘雅二医院·08-28 16:15
中国全球首发
靶向 ANGPTL3 的 CRISPR-Cas9 基因编辑药物 CTX310 的效应持久性
Durability of Effects of CTX310, a CRISPR-Cas9 Gene Editing Targeting ANGPTL3
Luke Joseph Laffin · 讲者 · Cleveland Clinic·08-28 16:15
全球首发
AAV8 介导的基因治疗用于纯合子家族性高胆固醇血症
AAV8-mediated gene therapy for homozygous familial hypercholesterolemia
Ting Li · 讲者 · 西安交通大学第一附属医院·08-28 16:15
中国全球首发
单次给药 Kylo-11 后超长时间降低 Lp(a):首个人体研究的最终数据
Extremely Long Duration Lp(a) Reduction Following a Single Dose of Kylo-11: Final Data from a First-in-Human Study
Ashish Sarraju · 讲者 · Cleveland Clinic·08-28 16:15
全球首发
Hot Line
HOT LINE 2(全球首发专场)
HOT LINE 2
时间08-29 08:15
主席Anne Tybjaerg-Hansen; Constantinos Davos
STAREE:他汀类药物减少老年人事件
STAREE: Statins for Reducing Events in the Elderly
Sophia Zoungas · 讲者 · The George Institute for Global Health·08-29 08:15
全球首发
AMUNDSEN:急性心肌梗死 PCI 前使用依洛尤单抗
AMUNDSEN: Evolocumab Before Percutaneous Coronary Intervention for Acute Myocardial Infarction
Gilles Montalescot · 讲者 · Sorbonne University·08-29 08:15
全球首发
TRANQUILITY:帕西贝奇图(IL-6 配体单抗)每月与每季度给药靶向高危心血管风险慢性肾脏病炎症的疗效
TRANQUILITY: Efficacy of monthly and quarterly dosing of pacibekitug (IL-6 ligand mAb) targeting inflammation in CKD with high cardiovascular risk
Deepak Bhatt · 讲者 · Icahn School of Medicine at Mount Sinai·08-29 08:15
全球首发
REACT——成人一生中无症状动脉粥样硬化的患病率
REACT - Prevalence of silent atherosclerosis across adult life
Henning Bundgaard · 讲者 · Rigshospitalet·08-29 08:15
全球首发
ENRICH-AF:颅内出血存活房颤患者使用艾多沙班
ENRICH-AF: Edoxaban in intracranial hemorrhage survivors with atrial fibrillation
Ashkan Shoamanesh · 讲者 · McMaster University·08-29 08:15
全球首发
DAN-RSV:RSVpreF 疫苗预防心肺疾病住院
DAN-RSV: RSVpreF vaccine for preventing cardiorespiratory hospitalisations
Tor Biering-Sorensen · 讲者 · Gentofte University Hospital·08-29 08:15
全球首发
02中国专家参与场次China Faculty3 场
中国专家参与的报告
血脂管理 · 3 项中国专家报告
基于机器学习与血流动力学特征的临床决策支持系统用于基层个体化、符合指南的降压治疗(LIGHT-precision)
Machine learning and hemodynamic profile-based clinical decision support systems for personalized guideline-concordant antihypertensive treatment in primary care (LIGHT-precision)
Xin Zheng · 讲者 · 中国医学科学院阜外医院·08-30 08:15
中国全球首发
口服 HRS-5346(新型小分子脂蛋白(a) 抑制剂)用于脂蛋白(a) 升高且高心血管风险的成人:2 期随机双盲研究
Oral HRS-5346, a novel small molecule lipoprotein(a) inhibitor, in adults at high cardiovascular risk with elevated lipoprotein(a): a phase 2, randomized, double-blind study
Dan Zhu · 讲者 · 北京大学第三医院·08-31 08:15
中国全球首发
评估 VSA003 注射液治疗中国纯合子家族性高胆固醇血症(HoFH)青少年与成人疗效和安全性的 3 期临床试验
A phase 3 clinical trial to evaluate the efficacy and safety of vsa003 injection in chinese adolescents and adults with homozygous familial hypercholesterolaemia (hofh)
Zhuang Tian · 讲者 · 北京协和医院·08-31 08:15
中国全球首发
其他 · 2 项中国专家报告
血管生成素样蛋白 3 抗体 rivocibart 治疗纯合子家族性高胆固醇血症
Angiopoietin-like 3 antibody rivocibart for homozygous familial hypercholesterolemia
Daoquan Peng · 讲者 · 中南大学湘雅二医院·08-28 16:15
中国全球首发
AAV8 介导的基因治疗用于纯合子家族性高胆固醇血症
AAV8-mediated gene therapy for homozygous familial hypercholesterolemia
Ting Li · 讲者 · 西安交通大学第一附属医院·08-28 16:15
中国全球首发
03本领域中国研究China Abstracts101 篇
研究标题第一作者所在机构
肥胖 · 16 篇
基于MRI的身体成分预测新发2型糖尿病
MRI-based body composition predicts incident type 2 diabetes mellitus
08-28 13:15
Shuang Zhang中国医学科学院北京协和医学院阜外医院
体重指数与急性心肌梗死患者短期结局的性别特异性关联
Sex-specific associations between body mass index and short-term outcomes in patients with acute myocardial infarction
08-28 13:15
Kang-Yin Chen天津医科大学第二医院
1999至2023年美国肥胖成人心血管死亡率趋势与差异
Trends and disparities of cardiovascular mortality among adults with obesity in the United States from 1999 to 2023
08-28 13:15
Jing Gao天津市胸科医院
高血压合并肥胖与新发心力衰竭风险:两项前瞻性队列研究的启示
Concurrent hypertension and obesity and the risk of incident heart failure: insights from two prospective cohort studies
08-28 16:15
Rongchong Huang首都医科大学附属北京友谊医院
将久坐时间重新分配给体力活动对不同代谢肥胖表型房颤的差异化获益:前瞻性队列研究
Differential benefits of reallocating sedentary time to physical activity on atrial fibrillation across metabolic obesity phenotypes: a prospective cohort study
08-28 16:15
Boning Zhou中国医学科学院北京协和医学院阜外医院
BMI与ACS院内死亡率的关系:中国心血管协会胸痛中心注册研究的结果
The relationship between BMI and ACS in-hospital mortality: findings from the Chinese Cardiovascular Association-Chest Pain Center Registry
08-29 10:45
Tongtong Zang复旦大学附属中山医院
非ST段抬高型心肌梗死患者体重指数与全因死亡的关联
Association between body mass index and all-cause mortality in patients with non-ST-segment-elevation myocardial infarction
08-29 11:35
Jing Gao天津市胸科医院
身体圆度指数与全因死亡及心血管疾病的关联:PURE-中国研究
Associations of body roundness index with with all-cause mortality and cardiovascular diseases: the prospective urban rural epidemiology (PURE)-China study
08-29 16:15
Lingqian Hu中国医学科学院北京协和医学院阜外医院
从儿童期到成年中期BMI累积负担与亚临床心血管结局:心血管危险因素的中介作用
Cumulative burden of body mass index from childhood to mid-adulthood in relation to subclinical cardiovascular outcomes: the mediating role of cardiovascular risk factors
08-29 16:15
Tongshuai Guo西安交通大学第一附属医院
细化心血管-肾脏-代谢综合征0-3期标准:全国NHANES队列中过度肥胖的增量重分层价值
Refining the criteria of cardiovascular-kidney-metabolic syndrome stage 0-3: the incremental reclassification value of excessive adiposity in a nationwide NHANES cohort
08-29 16:15
Haixu Yu北京积水潭医院
内脏肥胖相关代谢与炎症特征独立于BMI识别晚期CKM 4期
Visceral adiposity–associated metabolomic and inflammatory signatures identify advanced CKM stage 4 independent of BMI
08-29 16:15
Chi-Hsiao Yeh林口长庚纪念医院
腹型肥胖较全身性肥胖更早、更高地增加CKM综合征风险:NHANES横断面研究
Abdominal obesity leads to earlier and higher CKM syndrome risk than general obesity: a cross-sectional NHANES study
08-30 10:45
Qian-Hui Tai西安交通大学第一附属医院
从儿童期到成年期的长期BMI负担及其变异性与中年心血管-肾脏-代谢综合征:36年队列研究
Long-term BMI burden, its variability from childhood to adulthood and cardiovascular-kidney-metabolic syndrome in midlife: a 36-year cohort study
08-30 11:15
Guilin Hu西安交通大学第一附属医院
累积中心性肥胖指数预测中年靶器官损害的比较:31年队列研究
Comparison of cumulative central obesity indices for predicting midlife target organ damage: a 31-year Cohort Study
08-31 08:15
Qian-Hui Tai西安交通大学第一附属医院
低握力与腹型肥胖对主要心血管事件的联合影响:PURE-中国队列分析
Joint effects of low grip strength and abdominal obesity on major cardiovascular events: an analysis of the prospective urban rural epidemiology (PURE)-China cohort study
08-31 08:15
Chilie Danzeng国家心血管病中心、阜外医院心血管疾病国家重点实验室
甘油三酯-葡萄糖指数及其与人体测量肥胖指标的组合对中国人群MAFLD的显著预测
Triglyceride glucose index and its combination with anthropometric obesity indicators are significant predictors of MAFLD among the Chinese population
08-31 08:15
Mingwei Wang杭州师范大学附属医院
生物标志物 · 14 篇
残余胆固醇与急性心肌损伤患者死亡率:回顾性队列研究
Remnant cholesterol and mortality in patients with acute myocardial injury: a retrospective cohort study
08-28 09:15
Linhao Liu天津医科大学总医院
胆固醇-高密度脂蛋白-葡萄糖指数预测心血管-肾脏-代谢综合征的发病、进展与预后:两大前瞻性队列证据
Cholesterol, high-density lipoprotein, and glucose index predict the onset, progression, and prognosis of cardiovascular-kidney-metabolic syndrome: evidence from two large prospective cohorts
08-28 14:15
Zehao Zhao首都医科大学附属北京安贞医院
FIB-4指数与心血管-肾脏-代谢综合征的分期特异性关联:人群研究
Stage specific associations between FIB-4 index and cardiovascular kidney metabolic syndrome: a population-based study
08-28 14:15
Pengxin Xie北京大学第三医院
外周血嗜酸性粒细胞计数与氯吡格雷治疗的冠心病患者血小板反应性的相关性:大样本队列研究
Correlation between peripheral blood eosinophil count and platelet reactivity in coronary heart disease patients treated with clopidogrel: a large-scale cohort study
08-28 15:15
Zihao Ke国家心血管病中心、阜外医院心血管疾病国家重点实验室
生物学年龄加速与心血管-肾脏-代谢综合征进展:PhenoAge与KDMAge的多队列比较分析
Biological age acceleration and progression of cardiovascular-kidney-metabolic syndrome: a multi-cohort comparative analysis of phenoage and KDMAge
08-28 16:05
Yitian Chen首都医科大学附属北京友谊医院
高敏C反应蛋白超越AHA PREVENT方程的心血管风险重分层改善:英国生物样本库研究
High-sensitivity C-reactive protein improves cardiovascular risk reclassification beyond the AHA PREVENT equations: a UK Biobank study
08-29 12:15
Yuzhe Yin国家心血管病中心、阜外医院心血管疾病国家重点实验室
CTI累积负担与动态轨迹与亚临床靶器官损害及心血管疾病的关系:两项纵向队列的发现
Cumulative burden and dynamic trajectories of the CTI in relation to subclinical organ damage and cardiovascular disease: findings from two longitudinal cohorts
08-29 15:15
Guilin Hu西安交通大学第一附属医院
九种血脂相关复合指数预测急性心肌梗死患者临床结局的头对头比较
Head-to-head comparison of nine lipid-related composite indices for predicting clinical outcomes in patients with acute myocardial infarction
08-29 17:30
Shao Qiang Qin天津医科大学第二医院
应激性高血糖比值与炎症-代谢-凝血特征对早发心肌梗死远期不良结局的联合关联
Joint association of stress hyperglycemia ratio and inflammatory-metabolic-coagulation profiles with long-term adverse outcomes in premature myocardial infarction
08-30 08:15
Jing Gao天津市胸科医院
基于CTI的肥胖指数对新发心血管疾病的比较表现:CHARLS的启示
Comparative performance of CTI-based adiposity indices for incident CVD: insights from CHARLS
08-30 09:15
Feiyu Zhang首都医科大学附属北京安贞医院
整合常规生物标志物的早发冠心病年轻患者2年MACCE预测模型的开发与验证:多中心研究
Development and validation of a 2-year MACCE prediction model incorporating routine biomarkers in young patients with premature coronary heart disease: a multicenter study
08-30 09:15
Jingjing Xu国家心血管病中心、阜外医院心血管疾病国家重点实验室
中国内脏脂肪指数与新发心肾代谢多病共存的关联:9年全国队列研究
Association of the Chinese visceral adiposity index with incident cardio-renal-metabolic multimorbidity: a 9-year nationwide cohort study
08-30 11:15
Ying Song国家心血管病中心、阜外医院心血管疾病国家重点实验室
MAF-5评分与cT1的心血管风险:英国生物样本库证据
MAF-5 score and cT1 for cardiovascular risk: evidence from UK Biobank
08-31 09:15
Jing Yang上海市徐汇区中心医院
系统炎症反应指数累积暴露与CKM综合征0-2期中老年人群全因死亡风险的关联
Relationship between cumulative exposure to systemic inflammation response index and risk of all-cause mortality in middle-aged and older adults with cardiovascular-kidney-metabolic syndrome stage 0–2
08-31 13:15
Rongchong Huang首都医科大学附属北京友谊医院
流行病学 · 9 篇
心血管疾病、死亡与常见健康决定因素的省际差异:PURE-中国研究的启示
Provincial differences in cardiovascular disease, deaths, and common health determinants: insights from the Prospective Urban Rural Epidemiology (PURE)-China study
08-28 08:15
Xin Liu阜外医院
意义未明克隆性造血与Y染色体嵌合缺失对男性全因及心血管死亡的联合关联
Joint association of clonal hematopoiesis of indeterminate potential and mosaic loss of Y chromosome with all-cause and cardiovascular mortality in men
08-28 11:15
Ying Sun上海市第九人民医院
饮用低钙水降低血管内皮细胞活力并增加急性心肌梗死风险
Low calcium in drinking water reduces vascular endothelial cell viability and increases the risk of acute myocardial infarction
08-28 11:15
Min Liu河南省人民医院
肌酐/胱抑素C标准化比值累积暴露与变化模式和CKM 0-3期成人新发心血管疾病的关联:CHARLS分析
Associations of cumulative exposure and change patterns of the normalised creatinine-to-cystatin C ratio with incident cardiovascular disease in CKM stage 0–3 adults: a CHARLS analysis
08-29 10:15
Beibei Du吉林大学中日联谊医院
全因与心血管特异性死亡率代际分化的社会经济不平等:比较纵向分析
Diverging socioeconomic inequalities in all-cause and cardiovascular -specific mortality across generations: a comparative longitudinal analysis
08-29 13:15
Feilong Chen国家心血管病中心、阜外医院心血管疾病国家重点实验室
非酒精性脂肪肝与心血管-肾脏-代谢综合征进展的关联:英国生物样本库与中国队列证据
Association between nonalcoholic fatty liver disease and cardiovascular-kidney-metabolic syndrome progression: evidence from UK biobank and Chinese cohort
08-29 16:15
Weilan Li首都医科大学附属北京友谊医院
动态生活方式轨迹、多基因遗传风险与冠心病发病:英国生物样本库纵向研究
Dynamic lifestyle trajectories, polygenic risk, and incident coronary artery disease: a longitudinal study in the UK biobank
08-30 10:15
Qiao Ling Hou首都医科大学
青年期心血管-肾脏-代谢综合征与后续主要不良心血管事件、全因死亡及中年CKM分期的关联
Association of Cardiovascular-Kidney-Metabolic syndrome in young adulthood with subsequent major adverse cardiovascular events, all-cause mortality, and midlife Cardiovascular-Kidney -Metabolic stages
08-30 12:15
Jia-Jie Wang同济大学附属同济医院
15–39岁人群缺血性心脏病全球负担变化趋势:下降、差异与2020年后逆转
Changing trends in the global burden of ischemic heart disease among individuals aged 15–39 years: decline, disparities, and a post-2020 reversal
08-31 12:15
Xiaoyan Yang首都医科大学附属北京朝阳医院
代谢综合征、胰岛素与胰岛素抵抗 · 8 篇
甘油三酯-葡萄糖体重指数与非酒精性脂肪肝人群2型糖尿病的关联
Association between triglyceride-glucose body mass index and type 2 diabetes mellitus in patients with non-alcoholic fatty liver disease
08-28 08:15
Mingwei Wang杭州师范大学附属医院
04企业卫星会Industry Symposia26 个系列
赞助商分布9 场 · AstraZeneca 8 场 · Daiichi Sankyo Europe GmbH 4 场 · Medscape Education Global 3 场 · Pfizer 2 场 · Amgen 2 场 · Boehringer Ingelheim 1 场 · Eli Lilly and Company 1 场 · Servier 1 场 · MSD
指南与标准1 个系列
AstraZeneca
心衰诊疗排障:真实世界中优化指南指导的药物治疗
Troubleshooting heart failure: optimising guideline-directed-medical therapy in real-world practice
日程08-30
心力衰竭排查:真实世界中优化指南指导的药物治疗
Troubleshooting heart failure: optimising guideline-directed-medical therapy in real-world practice
Christina Paitazoglou · 讲者 · University Heart Center、Aaron K F Wong · 讲者 · Princess of Wales Hospital
血脂管理10 个系列
Daiichi Sankyo Europe GmbH
2026 血脂管理:真正改变结局的决策
Lipid management in 2026: decisions that actually change outcomes
日程08-28
2026 年血脂管理:真正改变结局的决策
Lipid management in 2026: decisions that actually change outcomes
Dirk Westermann · 讲者 · University Heart Center Freiburg-Bad Krozingen、Ingo Eitel · 讲者 · University Heart Center 等 3 人
AstraZeneca
Reimagining low-density lipoprotein cholesterol management, driving meaningful action – LD
日程08-28
欢迎来到低密度脂蛋白胆固醇行动实验室
Welcome to the low-density lipoprotein cholesterol action lab
轮转 1——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 1 Action station A: what would you do next? Action station B: AI-powered cardiovascular risk detection Action station C: mapping missed opportunities and solutions
轮转 2——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 2 Action station A: what would you do next? Action station B: AI-powered cardiovascular risk detection Action station C: mapping missed opportunities and solutions
轮转 3——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 3 Action station A: what would you do next? Action station B: AI-powered cardiovascular risk detection Action station C: mapping missed opportunities and solutions
低密度脂蛋白胆固醇行动计划
The low-density lipoprotein cholesterol action plan
Amgen
脂蛋白(a) 与心血管疾病:紧跟进展与新认识
Lipoprotein(a) in cardiovascular disease: keeping up the pace – new insights
日程08-28
欢迎与介绍
Welcome and introduction
Kausik K Ray · 讲者 · Imperial College London
Lp(a) 证据的新洞见与迎接靶向 Lp(a) 的未来
New insights in Lp(a) evidence and preparing for Lp(a) targeted future
Pia Kamstrup · 讲者 · Copenhagen University Hospital
实施系统性脂蛋白(a)检测是否具有成本效益?
Would it be cost-effective to implement systematic Lp(a)-testing?
Florian Kronenberg · 讲者 · Medical University of Innsbruck
脂蛋白(a) 与心血管疾病:紧跟步伐——新洞见讨论
Lipoprotein(a) in cardiovascular disease: keeping up the pace – new insights - discussion
会议评估 / 核心要点
Session evaluation / key learnings
AstraZeneca
从指南到行动:LDL-C 管理的真实世界路径辩论(系列共 3 场)
From guidelines to action - Debating real-world approaches to low-density lipoprotein cholesterol management
日程08-28、08-29、08-30
开场铺垫
Setting the scene
问题一:何时应强化治疗?
Question 1: when should treatment be intensified?
附:Where do you stand? Audience poll 1
问题二:为什么低密度脂蛋白胆固醇监测很重要?
Question 2: why does low-density lipoprotein cholesterol monitoring matter?
附:Where do you stand? Audience poll 2
专家亮相
Experts under the spotlight
附:Closing reflections and final audience poll
… 另 1 项讲题
Daiichi Sankyo Europe GmbH
斑块漫谈:从数字到降脂治疗的行动
Plaque talk: from numbers to action in lipid-lowering therapy
日程08-29
斑块对话:从数字到降脂治疗的行动
Plaque talk: from numbers to action in lipid-lowering therapy
Jolanta Siller-Matula · 讲者 · Medical University of Vienna、Yvonne Winhofer · 讲者 · Ordination
AstraZeneca
重构 LDL-C 管理,推动有意义的行动——LDL-C 行动实验室(系列共 3 场)
Reimagining low-density lipoprotein cholesterol management, driving meaningful action - LDL-C Action Lab
日程08-29、08-30
欢迎来到低密度脂蛋白胆固醇行动实验室
Welcome to the low-density lipoprotein cholesterol action lab
轮转 1——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 1 Action station A: what would you do next? Action station B: AI-powered cardiovascular risk detection Action station C: mapping missed opportunities and solutions
轮转 2——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 2 Action station A: what would you do next? Action station B: AI-powered cardiovascular risk detection Action station C: mapping missed opportunities and solutions
轮转 3——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 3 Action station A: what would you do next? Action station B: AI-powered cardiovascular risk detection Action station C: mapping missed opportunities and solutions
低密度脂蛋白胆固醇行动计划
The low-density lipoprotein cholesterol action plan
轮转 2——行动站 A:你下一步会怎么做?行动站 B:AI 驱动的心血管风险检测;行动站 C:梳理错失的机会与解决方案
Rotation 2 Action Station A: what would you do next? Action Station B: AI-powered cardiovascular risk detection Action Station C: mapping missed opportunities and solutions
… 另 1 项讲题
Daiichi Sankyo Europe GmbH
变革 LDL-C 管理:从准确风险评估到联合治疗
Transforming low-density lipoprotein cholesterol care: from correct risk assessment to combination therapies
日程08-29
欢迎与介绍
Welcome and introduction
Lale Tokgozoglu · 讲者 · Hacettepe University
正确的风险、正确的治疗:SANTORINI 研究的启示
Correct risk, correct treatment: insights from SANTORINI
Kausik K Ray · 讲者 · Imperial College London
结局试验证据:降低 LDL-C 与心血管获益
Evidence from outcome trials: low-density lipoprotein cholesterol reduction and cardiovascular benefit
Julia Brandts · 讲者 · University Hospital Frankfurt
从试验证据到真实世界实践:疗效、安全性特征与风险降低
From trial evidence to real-world practice: efficacy, safety profiles and risk reduction
J Wouter Jukema · 讲者 · Leiden University Medical Center
口服联合治疗:弥合 LDL-C 差距
Oral combination therapy: closing the low-density lipoprotein cholesterol gap
Lluis Masana · 讲者 · University Hospital Sant Joan de Reus
问答
Q&A
Lale Tokgozoglu · 评论员 · Hacettepe University、Kausik K Ray · 评论员 · Imperial College London 等 5 人
… 另 1 项讲题
Daiichi Sankyo Europe GmbH
贝派地酸融入临床实践:不同治疗场景下的 LDL-C 降幅
Integrating bempedoic acid into clinical practice: effectiveness in LDL-C reduction across treatment settings
日程08-29
将贝派地酸融入临床实践:不同治疗场景中降低 LDL-C 的有效性
Integrating bempedoic acid into clinical practice: effectiveness in LDL-C reduction across treatment settings
Alberico Catapano · 讲者 · IRCCS、Pasquale Perrone-Filardi · 讲者 · University of Naples Federico II
Medscape Education Global
血脂管理新篇章:拓展治疗边界
A new chapter in lipid control: expanding the therapeutic horizon
日程08-29
设定背景:高危患者的未满足需求
Setting the stage: the unmet need in high-risk patients
Kausik K Ray · 讲者 · Imperial College London
从逐步到迅速:早期启动联合治疗的理由
From stepwise to swift: the rationale for early initiation of combination therapy
Klaus G Parhofer · 讲者 · Ludwig Maximilians University
血脂控制的新篇章:科学
A new chapter for lipid control: the science
Ulrich Laufs · 讲者 · University Hospital Leipzig
血脂控制的新篇章:证据
A new chapter for lipid control: the evidence
Erin Michos · 讲者 · The Johns Hopkins University School of Medicine
展望血脂异常管理的未来——讨论
Envisioning the future of dyslipidaemia management - discussion
Kausik K Ray · 评论员 · Imperial College London、Ulrich Laufs · 评论员 · University Hospital Leipzig 等 4 人
闭幕致辞与 EBAC 评估
Closing remarks and EBAC evaluation
Kausik K Ray · 讲者 · Imperial College London
Daiichi Sankyo Europe GmbH
2026 血脂管理:真正改变结局的决策——病例讨论
Lipid management in 2026: decisions that actually change outcomes - a case-based discussion
日程08-29
2026 年血脂管理:真正改变结局的决策——基于病例的讨论
Lipid management in 2026: decisions that actually change outcomes - a case-based discussion
Daniel Duerschmied · 讲者 · University Medical Centre of Mannheim、Andrea Baessler · 讲者 · University Hospital Regensburg 等 3 人
综合与其他15 个系列
Eli Lilly and Company
隐匿风险,明确指引:动脉粥样硬化性心血管病的卓越预防策略
Hidden risk, clear guidance: strategies for excellence in atherosclerotic cardiovascular disease (ASCVD) prevention
日程08-28
引言与开场投票
Introduction and opening poll
Florian Kronenberg · 讲者 · Medical University of Innsbruck
超越标准危险因素——识别隐匿 ASCVD 风险与 Lp(a) 的作用
Beyond standard risk factors - identifying hidden ASCVD risk and recognising the role of Lp(a)
Lale Tokgozoglu · 讲者 · Hacettepe University
从危险分层到行动——通过循证且以患者为中心的 ASCVD 管理强化预防
From risk stratification to action — intensifying prevention through evidence-based and patient-centered ASCVD management
Klaus G Parhofer · 讲者 · Ludwig Maximilians University
互动讨论:在实践中应用 Lp(a) 指导的危险分层与治疗强化
Interactive discussion: applying Lp(a)-informed risk stratification and treatment intensification in practice
Florian Kronenberg · 讲者 · Medical University of Innsbruck、Lale Tokgozoglu · 讲者 · Hacettepe University 等 3 人
总结与闭幕
Summary & closure
Florian Kronenberg · 讲者 · Medical University of Innsbruck
Medscape Education Global
家族性乳糜微粒血症综合征的临床表现:提升识别、诊断与管理
The clinical face of familial chylomicronemia syndrome: improving recognition, diagnosis, and management
日程08-28
引言与概述
Introduction and overview
Gerald Watts · 讲者 · University of Western Australia
识别临床型家族性乳糜微粒血症综合征:"那个被所有人认为只是不依从的患者"
Recognising clinical familial chylomicronemia syndrome: "the patient everyone thought was just noncompliant"
Kausik K Ray · 讲者 · Imperial College London
基于临床标准诊断家族性乳糜微粒血症综合征
Diagnosing familial chylomicronemia syndrome based on clinical criteria
Ioanna Gouni-Berthold · 讲者 · University of Cologne
家族性乳糜微粒血症综合征治疗的新时代:“现在有何变化?”
A new treatment era for familial chylomicronemia syndrome: “what changes now?”
Gerald Watts · 讲者 · University of Western Australia
展望未来靶点
Looking ahead at future targets
Gerald Watts · 指定讲者 · University of Western Australia
要点回顾、听众问答与 EBAC 评估
Key takeaways, audience Q&A, and EBAC evaluation
Gerald Watts · 评论员 · University of Western Australia、Ioanna Gouni-Berthold · 评论员 · University of Cologne 等 3 人
Daiichi Sankyo Europe GmbH
心脏康复实践:连接证据与患者照护
Cardiac rehabilitation in practice: bridging evidence and patient care
日程08-28
心脏康复实践:连接证据与患者照护
Cardiac rehabilitation in practice: bridging evidence and patient care
Sofie Verstreken · 讲者 · Gent University Hospital、Gabriela Flores Vivian · 讲者 · Erasme Hospital 等 3 人
Amgen
心血管代谢风险:重建失衡的系统
Cardiometabolic risk: balancing the unstable system
日程08-28
欢迎与学习目标——作为不稳定系统的心血管代谢风险
Welcome and learning objectives - cardiometabolic risk as an unstable system
Mamas Mamas · 讲者 · Keele University
心血管风险评估与管理中的应做、不应做与大胆尝试
Do’s, don’ts and dares in cardiovascular risk assessment and management
Erik Stroes · 讲者 · AmsterdamUMC location AMC
从证据到地平线:试验、治疗前沿与精准预防
From evidence to horizon: trials, therapeutic frontiers and precision prevention
LDL-C 尽早还是更早
LDL-C early or earlier still
Marc Sabatine · 讲者 · Brigham and Women's Hospital, Harvard Medical School
超越 LDL-C:其他危险因素的分量
Beyond LDL-C the weight of other risk factors
Erin Bohula · 讲者 · Brigham and Women's Hospital
最后的刺痛
The sting in the tail
Michelle O'donoghue · 讲者 · Boston, United States of America
… 另 2 项讲题
Daiichi Sankyo Europe GmbH
口服联合治疗的真实世界洞察:贝派地酸的患者特征与疗效
Real-world insights into oral combination therapy: patient characteristics and effectiveness of bempedoic acid
日程08-28
口服联合治疗的真实世界见解:贝派地酸的临床特征与有效性
Real-world insights into oral combination therapy: patient characteristics and effectiveness of bempedoic acid
Marcello Arca · 讲者 · Umberto I Hospital、Egidio Imbalzano · 讲者 · University of Messina
Medscape Education Global
揭示病毒触发因素:成人免疫接种与心血管风险机制——病例探讨
Unmasking viral triggers: adult immunisation and the mechanisms of cardiovascular risk - a case-based exploration
日程08-28
欢迎与介绍
Welcome and introduction
Peter Libby · 讲者 · Mass General Brigham
隐藏的敌人——病毒感染机制与心血管风险
The hidden enemy - mechanisms of viral infection and cardiovascular risk
Wayne Ghesquiere · 讲者 · Canada, Canada
疫苗作为第四支柱——数据与建议
The vaccine as the fourth pillar - data and recommendations
Emmanuelle Berthelot · 讲者 · Hopital Bicetre
识别易损患者——基于病例的实施
Identifying the vulnerable patient - case-based implementation
Maja Cikes · 讲者 · University Hospital Centre Zagreb
问答、总结与 EBAC 评估
Q&A, conclusion, and EBAC evaluation
Peter Libby · 评论员 · Mass General Brigham
Pfizer
不只是呼吸道病毒:RSV、心血管风险与预防的必要性
More than a respiratory virus: respiratory syncytial virus, cardiovascular risk, and the case for prevention
日程08-29
为什么呼吸道合胞病毒在心脏病学中很重要:开场铺垫
Why respiratory syncytial virus matters in cardiology: setting the scene
Bettina Heidecker · 讲者 · Charite University Hospital
呼吸道感染未被认识的心血管后果
The unrecognised cardiovascular consequences of respiratory infection
Peter Libby · 讲者 · Mass General Brigham
呼吸道合胞病毒疫苗接种的真实世界证据:DAN-RSV 研究
Real-world evidence on respiratory syncytial virus vaccination : the DAN-RSV study
Tor Biering-Sorensen · 讲者 · Gentofte University Hospital
如何帮助患者预防呼吸道合胞病毒疾病:将证据转化为心血管实践
How to help prevent respiratory syncytial virus disease in your patients: translating evidence into cardiovascular practice
Bettina Heidecker · 讲者 · Charite University Hospital
核心要点与行动号召
Key take‑home messages and call to action
Bettina Heidecker · 讲者 · Charite University Hospital
Boehringer Ingelheim
通往心血管健康之路:白蛋白尿作为关键心血管风险标志物(系列共 2 场)
The road to cardiovascular health: albuminuria as a key cardiovascular risk marker
日程08-29、08-30
通往心血管健康之路:白蛋白尿作为关键心血管风险标志物
The road to cardiovascular health: albuminuria as a key cardiovascular risk marker
Nikolaus Marx · 讲者 · RWTH University Hospital Aachen
Servier
一个连续谱,一套策略:心血管代谢疾病的整体管理
One continuum, one strategy: managing cardiometabolic diseases as one
日程08-29
引言
Introduction
John Eric Deanfield · 讲者 · University College London
早期心血管代谢控制:从源头降低风险
Early cardiometabolic control: reducing risk from the start
Aleksander Prejbisz · 讲者 · National Institute of Cardiology、Maria Ramos · 讲者 · Escuela Hospital
治疗依从性差是下一个心血管危险因素吗?
Is poor adherence to treatment the next cardiovascular risk factor?
Khadija Hafidh · 讲者 · Dubai Healthcare City
一个连续体、一个策略:将心血管代谢疾病作为整体管理——讨论与问答
One continuum, one strategy: managing cardiometabolic diseases as one - Discussion and Q&A
一个连续体、一个策略:将心血管代谢疾病作为整体管理——总结
One continuum, one strategy: managing cardiometabolic diseases as one - Conclusion
Alta Schutte · 讲者 · The George Institute for Global Health
Pfizer
将呼吸道疾病疫苗接种纳入心血管照护
Integrating vaccination for prevention of respiratory disease into cardiovascular care
日程08-29
将预防呼吸道疾病的疫苗接种整合进心血管诊疗
Integrating vaccination for prevention of respiratory disease into cardiovascular care
Derek Connolly · 讲者 · Midland Metropolitan University Hospital
MSD
从风险到责任:多方对话回应心血管流行,纳入患者声音
From risk to responsibility: responding to the cardiovascular epidemic through a multi-stakeholder dialogue integrating patient voices
日程08-30
设定挑战
Setting the challenge
Borge Nordestgaard · 讲者 · Copenhagen University Hospital
临床视角:低密度脂蛋白讨论中还缺什么?
Clinical perspective: what’s missing in low-density lipoprotein discussions
Michal Vrablik · 讲者 · Charles University of Prague
患者倡导者视角
Patient advocate perspective
Jens Naeumann · 讲者 · Germany、Chloe Green · 讲者 · United Kingdom of Great Britain & Northern Ireland 等 3 人
专家讨论:落实实践变革
Panel discussion: implementing practice change
Borge Nordestgaard · 评论员 · Copenhagen University Hospital、Michal Vrabel · 评论员 · Kardiocentrum Saca 等 5 人
明确的行动号召
Clear call to action
Borge Nordestgaard · 讲者 · Copenhagen University Hospital
Pfizer
DAN-RSV 研究聚焦:证据、解读与临床意义
The DAN-RSV trial in focus: evidence, interpretation, and clinical relevance
日程08-30
聚焦 DAN-RSV 试验:证据、解读与临床相关性
The DAN-RSV trial in focus: evidence, interpretation, and clinical relevance
Tor Biering-Sorensen · 讲者 · Gentofte University Hospital
Medscape Education Global
数据说话:流感疫苗接种心脏保护作用的临床证据
The data speaks: clinical evidence for cardioprotection through influenza vaccination
日程08-30
欢迎与介绍:免疫接种作为心血管保护
Welcome and introduction: immunisation as cardiovascular protection
Ulf Landmesser · 讲者 · Charite University Hospital、Holly Seale · 讲者 · University of New South Wales Sydney
炎症浪潮:流感如何损害心脏
The inflammatory surge: how influenza damages the heart
Ulf Landmesser · 讲者 · Charite University Hospital
病例 1——心衰守护者:预防失代偿
Case 1 – The heart failure defender: preventing decompensation
Christian Eugen Mueller · 讲者 · University Hospital Basel
病例 2——克服万难:免疫功能低下老年人的保护
Case 2 – Against all odds: protection for the immunocompromised older adult
Oana Sandulescu · 讲者 · University of Medicine and Pharmacy Carol Davila
问答、总结致辞与 EBAC 评估
Q&A, concluding remarks, and EBAC evaluation
Ulf Landmesser · 评论员 · Charite University Hospital、Holly Seale · 评论员 · University of New South Wales Sydney
AstraZeneca
高钾血症管理入门:助力 RAAS 抑制剂优化使用
Hyperkalaemia management 101: supporting renin-angiotensin-aldosterone system inhibitor optimisation
日程08-30
高钾血症管理入门:支持肾素-血管紧张素-醛固酮系统抑制剂优化
Hyperkalaemia management 101: supporting renin-angiotensin-aldosterone system inhibitor optimisation
Clara Bonanad Lozano · 讲者 · Research Foundation Hospital of Valencia (INCLIVA)、Aaron K F Wong · 讲者 · Princess of Wales Hospital
Daiichi Sankyo Europe GmbH
心血管预防门诊实践:真实世界经验、患者获益与多学科协作——专家最佳实践交流
Cardiovascular prevention clinics in practice: real-world experience, patient benefits, and multidisciplinary collaboration - a best practice exchange between experts
日程08-31
心血管预防门诊实践:真实世界经验、患者获益与多学科协作——专家最佳实践交流
Cardiovascular prevention clinics in practice: real-world experience, patient benefits, and multidisciplinary collaboration - a best practice exchange between experts
Fabian Demeure · 讲者 · CHU UCL Namur、Tijs Bringmans · 讲者 · AZ Sint Maarten
企业卫星会内容由赞助方支持,此处仅作学术日程信息陈列,不代表编辑立场。
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AMUNDSEN
AMUNDSEN: Evolocumab Before Percutaneous Coronary Intervention for Acute Myocardial Infarction
已有发表积累
研究
注册号
NCT06364124
状态
未知
期别/类型
无期别 期 · INTERVENTIONAL
入组
84 人(1 国)
启动
2023-06-01
主要研究者
Gilles Montalescot · Sorbonne University - Paris, France
主要终点
LDL-C水平自基线至出院和第30天的平均百分比变化
文章
American heart journal · 2026 · PMID 41192637
The AMUNDSEN trial will provide critical insights into the potential benefits of early PCSK9 inhibition in high-risk MI patients undergoing PCI.
BetaBlocker discontinuation in patients with chronic coronary syndrome, prior myocardial infarction
BetaBlocker discontinuation in patients with chronic coronary syndrome, prior myocardial infarction: a pooled analysis of the ABYSS and SMART-DECISION randomised trials.
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Cardiometabolic parameters by the degree of maintenance of weight reduction in tirzepatide-treated adults with obesity
Cardiometabolic parameters by the degree of maintenance of weight reduction in tirzepatide-treated adults with obesity: post hoc study of SURMOUNT MAINTAIN Trial
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
DAN-RSV
DAN-RSV: RSVpreF vaccine for preventing cardiorespiratory hospitalisations
注册记录待核
文章
JAMA · 2025 · PMID 40884493
Respiratory syncytial virus (RSV) infection is linked to elevated cardiovascular risk, particularly in individuals with preexisting cardiovascular disease (CVD). A bivalent RSV prefusion F protein (RSVpreF) vaccine was recently approved for preventing RSV-related lower respiratory tract illness, but its effectiveness a…
Journal of the American College of Cardiology · 2025 · PMID 40884521
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
ENRICH-AF
ENRICH-AF: Edoxaban in intracranial hemorrhage survivors with atrial fibrillation
已有发表积累
研究
注册号
NCT03950076
状态
入组完成·随访中
期别/类型
PHASE4 期 · INTERVENTIONAL
入组
948 人(15 国)
启动
2019-09-20
主要研究者
Ashkan Shoamanesh · McMaster University - Hamilton, Canada
主要终点
卒中或全身性栓塞 ① 大出血
文章
Scientific reports · 2024 · PMID 38942790
Subclinical leaflet thrombosis (SLT) can be one of the causes of transcatheter heart valve (THV) failure after transcatheter aortic valve implantation (TAVI). We sought to clarify the formation process of SLT and thrombogenicity during the perioperative period of TAVI. This multicenter, prospective, single-arm interven…
Effects of Evolocumab on Fatal Outcomes in Patients Without a Prior Myocardial Infarction or Stroke
Effects of Evolocumab on Fatal Outcomes in Patients Without a Prior Myocardial Infarction or Stroke : Pre-specified Analysis of the VESALIUS-CV Trial
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Extremely Long Duration Lp(a) Reduction Following a Single Dose of Kylo-11
Extremely Long Duration Lp(a) Reduction Following a Single Dose of Kylo-11: Final Data from a First-in-Human Study
全球首发信号
研究
注册号
NCT06478693
状态
入组中
期别/类型
I 期 · INTERVENTIONAL
入组
70 人(3 国)
启动
2024-07-01
主要研究者
Ashish Sarraju · Cleveland Clinic - Cleveland, United States of America
主要终点
不良事件的类型、发生率和严重程度 ① 推荐II期剂量(RP2D) ① 最佳生物剂量(OBD)
首发
会前无公开结果文献 —— ESC 2026 现场即全球首发的报道窗口
Head-to-head comparison of inclisiran vs bempedoic acid for LDL C lowering in patients with high and very high cardiovascular risk
Head-to-head comparison of inclisiran vs bempedoic acid for LDL C lowering in patients with high and very high cardiovascular risk: Results from the phase 4 VICTORION-CHALLENGE trial
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
High-Intensity Interval Training Reduces 10-Year Mortality in Older Adults
High-Intensity Interval Training Reduces 10-Year Mortality in Older Adults: The Generation 100 Randomized Controlled Trial
全球首发信号
研究
注册号
NCT04262336
状态
已随访完成
期别/类型
I 期 · INTERVENTIONAL
入组
22 人(2 国)
启动
2020-02-21
主要研究者
Sindre Midttun · Norwegian University of Science and Technology - Trondheim, Norway
主要终点
出现治疗中出现的不良事件(TEAEs)和/或临床实验室、生命体征、心电图较基线异常变化的患者数
首发
会前无公开结果文献 —— ESC 2026 现场即全球首发的报道窗口
A phase 3 clinical trial to evaluate the
A phase 3 clinical trial to evaluate the efficacy and safety of vsa003 injection in chinese adolescents and adults with homozygous familial hypercholesterolaemia (hofh)
全球首发信号
研究
注册号
NCT06712771
状态
入组完成·随访中
期别/类型
III 期 · INTERVENTIONAL
入组
46 人(1 国)
启动
2024-11-27
主要研究者
Zhuang Tian · Peking Union Medical College Hospital - Beijing, China
主要终点
第6个月血清LDL-C自基线百分比变化
首发
会前无公开结果文献 —— ESC 2026 现场即全球首发的报道窗口
AAV8-mediated gene therapy for homozygou
AAV8-mediated gene therapy for homozygous familial hypercholesterolemia
已有发表积累
研究
注册号
NCT02651675
状态
已终止
期别/类型
I,II 期 · INTERVENTIONAL
入组
9 人(4 国)
启动
2016-03
主要研究者
Ting Li · the First Affiliated Hospital of Xi'an Jiaotong University - Xi'an, China
主要终点
试验药物相关不良事件的参与者数
文章
Stem cell research & therapy · 2019 · PMID 31358055
Our work provides the first LDLR-null FH cell model and its corrected counterpart to study the regulation of cholesterol metabolism and host determinants of HCV life cycle, and a platform to screen drugs for treating dyslipidemia and HCV infection.
Human gene therapy · 2025 · PMID 40462752
Angiopoietin-like 3 antibody rivocibart
Angiopoietin-like 3 antibody rivocibart for homozygous familial hypercholesterolemia
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Durability of Effects of CTX310, a CRISP
Durability of Effects of CTX310, a CRISPR-Cas9 Gene Editing Targeting ANGPTL3
注册记录待核
文章
Circulation · 2023 · PMID 36314243
VERVE-101 was well tolerated in nonhuman primates and led to 83% lower blood PCSK9 protein and 69% lower low-density lipoprotein cholesterol with durable effects up to 476 days after dosing. These results have supported the initiation of a first-in-human clinical trial in patients with heterozygous familial hypercholesterolemia and atherosclerotic cardiovascular disease.
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
Effect on Oxidized Phospholipids of Lepo
Effect on Oxidized Phospholipids of Lepodisiran, an Extended Duration siRNA Targeting Lipoprotein(a)
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Machine learning and hemodynamic profile
Machine learning and hemodynamic profile-based clinical decision support systems for personalized guideline-concordant antihypertensive treatment in primary care (LIGHT-precision)
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Oral HRS-5346, a novel small molecule lipoprotein(a) inhibitor, in adults at high cardiovascular risk with elevated lipoprotein(a)
Oral HRS-5346, a novel small molecule lipoprotein(a) inhibitor, in adults at high cardiovascular risk with elevated lipoprotein(a): a phase 2, randomized, double-blind study
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Personal Plaque Threshold
The Personal Plaque Threshold: A Causal AI Biological World Model for Selecting Individualized LDL Targets to Personalize Cardiovascular Prevention
资料待补
数据缺口与信号
  • CT.gov 无注册记录匹配(观察性研究/本地注册试验可能未入 CT.gov)
  • 会前无同研究公开文献 → 结果全球首发,既往只有设计/方案文献或全无
Protocol-based early intensive lipid management in patients with acute coronary syndrome (BRIDGE)
Protocol-based early intensive lipid management in patients with acute coronary syndrome (BRIDGE): A multicenter prospective cluster-randomized controlled trial
已有发表积累
研究
注册号
NCT01049217
状态
已终止
期别/类型
III 期 · INTERVENTIONAL
入组
377 人(9 国)
启动
2010-04
主要研究者
Kazuma Oyama · Tohoku University - Sendai, Japan
主要终点
终点时(最长16周)平均疼痛评分较基线变化
文章
Journal of clinical lipidology · 2026 · PMID 42562562
A family-centered strategy combining lifestyle counseling, dietary changes, and healthcare support can significantly improve lipid profiles in high-risk individuals. Scaled to the population level, such interventions could lower dyslipidemia rates and help prevent CVD in low- and middle-income countries.
Journal of cardiovascular development and disease · 2026 · PMID 42645847
REACT
REACT - Prevalence of silent atherosclerosis across adult life
已有发表积累
研究
注册号
NCT06692127
状态
入组完成·随访中
期别/类型
— · OBSERVATIONAL
入组
16,808 人(2 国)
启动
2024-11-27
主要研究者
Henning Bundgaard · Rigshospitalet - Copenhagen University Hospital - Copenhagen, Denmark
主要终点
无症状动脉粥样硬化(至少一处血管区域斑块)患病率
Risk of Ischemic Stroke With Beta-Blockers
Risk of Ischemic Stroke With Beta-Blockers: Evidence From Randomized Clinical Trials
全球首发信号
研究
注册号
NCT06147128
状态
未知
期别/类型
— · OBSERVATIONAL
入组
48 人(1 国)
启动
2023-08-10
主要研究者
Franz Messerli · Lucerne Cantonal Hospital - Luzern, Switzerland
主要终点
达芬奇机器人干式实验模型中血管损伤需开放转换的紧急场景下PBP培训与传统培训的比较
首发
会前无公开结果文献 —— ESC 2026 现场即全球首发的报道窗口
STAREE
STAREE: Statins for Reducing Events in the Elderly
已有发表积累
研究
注册号
NCT04262206
状态
入组中
期别/类型
PHASE4 期 · INTERVENTIONAL
入组
20,000 人(2 国)
启动
2020-09-01
主要研究者
Sophia Zoungas · The George Institute for Global Health - Sydney, Australia
主要终点
未诊断新发痴呆的患者数 ① 无持续残疾的患者数
文章
BMJ open · 2023 · PMID 37012015
The world is undergoing a demographic transition to an older population. Preventive healthcare has reduced the burden of chronic illness at younger ages but there is limited evidence that these advances can improve health at older ages. Statins are one class of drug with the potential to prevent or delay the onset of s…
TRANQUILITY
TRANQUILITY: Efficacy of monthly and quarterly dosing of pacibekitug (IL-6 ligand mAb) targeting inflammation in CKD with high cardiovascular risk
全球首发信号
研究
注册号
NCT06362759
状态
已随访完成
期别/类型
II 期 · INTERVENTIONAL
入组
143 人(1 国)
启动
2024-05-15
主要研究者
Deepak Bhatt · Icahn School of Medicine at Mount Sinai - New York City, United States of America
主要终点
至第90天高敏C反应蛋白(hs-CRP)自基线时间平均百分比变化
首发
会前无公开结果文献 —— ESC 2026 现场即全球首发的报道窗口