心血管药理学

Ticalicibart monthly as add-on therapy to statins for nonfamilial hypercholesterolemia: the randomized, phase 3 TIMER trial

HRS-7249, a small interfering RNA targeting apolipoprotein C3, in healthy subjects

Real-world outcomes of biweekly and monthly alirocumab regimens: a population-based analysis

Safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-1301, an oral PCSK9 inhibitor, in healthy participants: a first-in-human, randomized, double-blind, placebo-controlled phaseⅠtrial

Efficacy and safety of recaticimab in lowering atherogenic lipids in patients with and without coronary artery disease: a patient-level pooled analysis

LDL-c levels and clinical outcomes in acute myocardial infarction patients with prior ischemic stroke

Hyperuricemia risk in bempedoic acid-treated hyperlipidemic patients

Impact of inclisiran on the cardiometabolic–inflammatory index: a real-world observational study

Comparative effectiveness of probucol versus ezetimibe in statin-treated patients with established atherosclerotic cardiovascular disease

Evolocumab early reduces Interleukin-1β/Interleukin-17A and improves left ventricular function in ST-segment elevation myocardial infarction: an observational study in the real world

EDP167, an ANGPTL3-target siRNA, showed favorable safety and lipid-lowering potential in Chinese healthy adult volunteers and subjects with mild dyslipidemia

Statin therapy and 1-year mortality in non-ischaemic acute myocardial injury: a dual-cohort study

Preclinical study and evaluation of S016, a novel oral small-molecule PCSK9 inhibitor

Impact of stepwise dual antiplatelet therapy de-escalation in patients with high bleeding risk undergoing drug-coated balloon angioplasty: Insights from the REC-CAGEFREE II trial

Troponin-stratified outcomes of extended clopidogrel monotherapy versus dual antiplatelet therapy in acute coronary syndrome: insights from the OPT-BIRISK randomized trial

Ticagrelor versus clopidogrel in acute coronary syndrome patients with concurrent high ischemic and high bleeding risk after drug-eluting stent implantation

Bleeding and mortality risks after intravenous alteplase in stroke patients with prior dual antiplatelet therapy: a nationwide cohort study

Impact of stepwise dual antiplatelet therapy de-escalation according to body mass index in patients undergoing drug-coated balloon angioplasty: insights from the REC-CAGEFREE II trial

Evaluation of machine learning framework for personalized prediction of benefit from beta-blockers in myocardial infarction with preserved or mildly reduced ejection fraction

Metoprolol versus bisoprolol in patients with acute myocardial infarction: a target trial emulation study

β-blocker adherence trajectories and 5-year clinical outcomes in PCI-treated ACS patients with LVEF ≥50%: a group-based trajectory modeling analysis

Prognostic outcomes of SGLT2 inhibitors versus metformin in patients with type 2 diabetes and acute myocardial infarction

Semaglutide attenuates diabetic vascular calcification by enhancing autophagy and lysosomal function via targeting CPNE1

Non-vitamin K antagonist oral anticoagulants versus warfarin and the risk of cataract in patients with atrial fibrillation: A real-world cohort study

Prognostic impact of post-procedural low-molecular-weight heparin in high-bleeding risk patients undergoing pci for acute myocardial infarction

Mechanisms of TNF-α-mediated myocardial toxicity induced by CAR-T cell therapy

Potent and sustained blood pressure reduction with a novel small interfering RNA targeting hepatic angiotensinogen: results from a first-in-human, randomised, phase 1 study

STUB1 orchestrates mineralocorticoid receptor activation to promote aortic dissection